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Flatfish, such as the flounder, are among the few vertebrates that lack
approximate bilateral symmetry (symmetry in which structures to the left and
right of the body’s midline are mirror images). Most striking among the many
asymmetries evident in an adult flatfish is eye placement: before maturity one
eye migrates, so that in an adult flatfish both eyes are on the same side of the
head. While in most species with asymmetries virtually all adults share the same
asymmetry, members of the starry flounder species can be either left-eyed (both
eyes on the left side of head) or right-eyed. In the waters between the United
States and Japan, the starry flounder populations vary from about 50 percent
left-eyed off the United States West Coast, through about 70 percent left-eyed
halfway between the United States and Japan, to nearly 100 percent left-eyed off
the Japanese coast.
Biologists call this kind of gradual variation over a certain geographic
range a “cline” and interpret clines as strong indications that the variation is
adaptive, a response to environmental differences. For the starry flounder this
interpretation implies that a geometric difference (between fish that are mirror
images of one another) is adaptive, that left-eyedness in the Japanese starry
flounder has been selected for, which provokes a perplexing question: what is
the selective advantage in having both eyes on one side rather than on the
other?
The ease with which a fish can reverse the effect of the sidedness of its
eye asymmetry simply by turning around has caused biologists to study internal
anatomy, especially the optic nerves, for the answer. In all flatfish the optic
nerves cross, so that the right optic nerve is joined to the brain’s left side
and vice versa. This crossing introduces an asymmetry, as one optic nerve must
cross above or below the other. G. H. Parker reasoned that if, for example, a
flatfish’s left eye migrated when the right optic nerve was on top, there would
be a twisting of nerves, which might be mechanically disadvantageous. For starry
flounders, then, the left-eyed variety would be selected against, since in a
starry flounder the left optic nerve is uppermost.
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